David Cohen may refer to:

Academia

• David Cohen (historian) (1882–1967), Dutch historian, Holocaust survivor
• David Cohen (rabbi) (1887–1972), Rabbi, talmudist, philosopher, and kabbalist
• David Cohen (physicist) (born 1930), M.I.T. physicist
• David B. Cohen (psychologist) (1941–2004), American psychology professor
• David K. Cohen (1934–2020), American education theorist
• David Mark Cohen (1952–1997), playwriting professor at the University of Texas at Austin
• David William Cohen (born 1943), professor of history and anthropology

Business

• David Cohen (entrepreneur) (born 1968), American entrepreneur
• David Cohen (died 2002), founder of John's Bargain Store
• David Oliver Cohen (born 1980), American writer, actor and entrepreneur

Government and politics